A selection of publications on non-melanoma skin cancer & actinic keratosis

  • diagnosis
  • margin mapping
  • treatment monitoring

Non-melanoma skin cancer & actinic keratosis - Diagnosis

Updated January 2018

Themstrup, L., De Carvalho, N., Nielsen, S.M., Olsen, J., Ciardo, S., Schuh, S., Nørnberg, B.M.H., Welzel, J., Ulrich, M., Pellacani, G. and Jemec, G.B. (2017) "In vivo differentiation of common basal cell carcinoma subtypes by microvascular and structural imaging using dynamic optical coherence tomography." Experimental dermatology. Link

Holmes, J., von Braunmühl, T., Berking, C., Sattler, E., Ulrich, M., Reinhold, U., Kurzen, H., Dirschka, T., Kellner, C., Schuh, S. and Welzel, J. (2017) "Optical coherence tomography of basal cell carcinoma: influence of location, subtype, observer variability and image quality on diagnostic performance." British Journal of Dermatology. Link

Welzel, J. and Schuh, S. (2017) "Noninvasive diagnosis in dermatology."                                                                                                                           JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 15(10), pp.999-1016. Link

Rigel, D.S. and Farberg, A.S. (2017) "Non-Invasive Technologies for the Diagnosis and Management of Skin Cancer"                                                 E-Book (Vol. 35, No. 4). Elsevier Health Sciences. Link

Sigsgaard, V., Themstrup, L., Theut Riis, P., Olsen, J. and Jemec, G.B. (2017) "In vivo measurements of blood vessels’ distribution in non‐melanoma skin cancer by dynamic optical coherence tomography—a new quantitative measure?" Skin Research and Technology. Link

Themstrup, L., Pellacani, G., Welzel, J., Holmes, J., Jemec, G.B.E. and Ulrich, M. (2017)                                                                                                             "In vivo microvascular imaging of cutaneous actinic keratosis, Bowen's disease and squamous cell carcinoma using Dynamic optical coherence tomography." Journal of the European Academy of Dermatology and Venereology. Link

Friis, K.B.E., Themstrup, L. and Jemec, G.B.E. (2017) "Optical coherence tomography in the diagnosis of actinic keratosis—A systematic review" Photodiagnosis and Photodynamic Therapy, 18, pp.98-104. Link

Schuh, S., Holmes, J., Ulrich, M., Themstrup, L., Jemec, G.B., De Carvalho, N., Pellacani, G. and Welzel, J. (2017)                                                             "Imaging Blood Vessel Morphology in Skin: Dynamic Optical Coherence Tomography as a Novel Potential Diagnostic Tool in Dermatology." Dermatology and Therapy, pp.1-16. Link

Maher, N.G., Blumetti, T.P., Gomes, E.E., Cheng, H.M., Satgunaseelan, L., Lo, S., Rezze, G.G., Scolyer, R.A. and Guitera, P. (2016)                                       "Melanoma diagnosis may be a pitfall for optical coherence tomography assessment of equivocal amelanotic or hypomelanotic skin lesions."               British Journal of Dermatology. Link

Coleman, Andrew John, Thomas James Richardson, Guy Orchard, Ayesha Uddin, Min Joo Choi, and Katie Elizabeth Lacy.                                            "Histological correlates of optical coherence tomography in non‐melanoma skin cancer." Skin Research and Technology 19, no. 1 (2013): e10-e19. Link

Wahrlich, C., S. A. Alawi, S. Batz, J. W. Fluhr, J. Lademann, and M. Ulrich.                                                                                                                               "Assessment of a scoring system for Basal Cell Carcinoma with multi‐beam optical coherence tomography."                                                                        Journal of the European Academy of Dermatology and Venereology 29, no. 8 (2015): 1562-1569. Link

Ulrich, M., T. Braunmuehl, H. Kurzen, T. Dirschka, C. Kellner, E. Sattler, C. Berking, J. Welzel, and U. Reinhold. "The sensitivity and specificity of optical coherence tomography for the assisted diagnosis of non-pigmented basal cell carcinoma - an observational study"                                                             British Journal of Dermatology 173, no. 2 (2015): 428-435. Link

Cheng, H. M., and P. Guitera. "Systematic review of optical coherence tomography usage in the diagnosis and management of basal cell carcinoma."   British Journal of Dermatology 173, no. 6 (2015): 1371-1380. Link

Markowitz, Orit, Michelle Schwartz, Eleanor Feldman, Amanda Bienenfeld, Amy K. Bieber, Jeffery Ellis, Usha Alapati, Mark Lebwohl, and Daniel M. Siegel. “Evaluation of Optical Coherence Tomography as a Means of Identifying Earlier Stage Basal Cell Carcinomas while Reducing the Use of Diagnostic Biopsy” The Journal of clinical and aesthetic dermatology 8, no. 10 (2015): 14. Link

Schuh, S., Kaestle, R., Sattler, E. and Welzel, J. (2016)                                                                                                                                                                 "Comparison of different optical coherence tomography devices for diagnosis of non‐melanoma skin cancer." Skin Research and TechnologyLink

Schuh S, Kaestle R, Sattler EC, Welzel J. "Optical coherence tomography of actinic keratoses and basal cell carcinomas–differentiation by quantification of signal intensity and layer thickness." Journal of the European Academy of Dermatology and Venereology. (2016) Feb 1. Link

Cheng, H.M., Lo, S., Scolyer, R., Meekings, A., Carlos, G. and Guitera, P. (2016) "Accuracy of optical coherence tomography for the diagnosis of superficial basal cell carcinoma–a prospective, consecutive, cohort study of 168 cases." British Journal of Dermatology. Link

Markowitz, O., Schwartz, M., Minhas, S. and Siegel, D.M. (2016) "Speckle-variance optical coherence tomography: a novel approach to skin cancer characterization using vascular patterns." Dermatology Online Journal, 22(4). Link

Hussain, A.A., Themstrup, L., Nürnberg, B.M. and Jemec, G.B.E. (2016) "Adjunct use of optical coherence tomography increases the detection of recurrent basal cell carcinoma over clinical and dermoscopic examination alone". Photodiagnosis and photodynamic therapy, 14, pp.178-184. Link

Meekings, A., Utz, S., Ulrich, M., Bienenfeld, A., Nandanan, N., Fisher, J., McKenzie, G., Siegel, D.M., Feldman, E. and Markowitz, O. (2016)                "Differentiation of Basal Cell Carcinoma Subtypes in Multi-Beam Swept Source Optical Coherence Tomography (MSS-OCT)."                                            Journal of drugs in dermatology: JDD, 15(5), p.545. Link

Banzhaf, C. and Jemec, G.B. (2012) "Imaging granulomatous lesions with optical coherence tomography." Case reports in dermatology, 4(1), pp.14-18. Link

Hussain, Alia Arif, Lotte Themstrup, and Gregor Borut Ernst Jemec.                                                                                                                                                "Optical Coherence Tomography in the diagnosis of Basal Cell Carcinoma" Arch Archives of dermatological research 307, no. 1 (2015): 1-10. Link

Pelosini, L., Smith, H.B., Schofield, J.B., Meeckings, A., Dithal, A. and Khandwala, M. (2015)                                                                                                                   "A novel imaging approach to periocular basal cell carcinoma: in vivo optical coherence tomography and histological correlates." Eye. Link 

Reinholz, M., Gauglitz, G.G., Giehl, K., Braun‐Falco, M., Schwaiger, H., Schauber, J., Ruzicka, T., Berneburg, M. and Braunmühl, T. (2015)                 "Non‐invasive diagnosis of sweat gland dysplasia using optical coherence tomography and reflectance confocal microscopy in a family with anhidrotic ectodermal dysplasia (Christ–Siemens–Touraine syndrome)". Journal of the European Academy of Dermatology and Venereology. Link

Alawi, S. A., S. Batz, J. Röwert‐Huber, J. W. Fluhr, J. Lademann, and M. Ulrich. "Correlation of optical coherence tomography and histology in microcystic adnexal carcinoma: a case report." Skin Research and Technology 21, no. 1 (2015): 15-17. Link

 

Non-melanoma skin cancer & actinic keratosis - Margin mapping

Updated November 2017

De Carvalho, N., Schuh, S., Kindermann, N., Kästle, R., Holmes, J. and Welzel, J. (2017)                                                                                                 "Optical coherence tomography for margin definition of basal cell carcinoma before micrographic surgery—recommendations regarding the marking and scanning technique." Skin Research and Technology. Link

Rashed, D., Shah, D., Freeman, A., Cook, R.J., Hopper, C. and Perrett, C.M. (2017)                                                                                                               "Rapid ex vivo examination of Mohs specimens using optical coherence tomography." Photodiagnosis and Photodynamic Therapy. Link

Themstrup, L. and Jemec, G.B. (2014) "Optical coherence tomography and its role for delineating the thickness of keratinocyte dysplasia and neoplasia."    In Actinic Keratosis (Vol. 46, pp. 95-100). Karger Publishers. Link

Coleman, A.J., Penney, G.P., Richardson, T.J., Guyot, A., Choi, M.J., Sheth, N., Craythorne, E., Robson, A. and Mallipeddi, R. (2014)                      "Automated registration of optical coherence tomography and dermoscopy in the assessment of sub-clinical spread in basal cell carcinoma." Computer Aided Surgery, 19(1-3), pp.1-12. Link

Duffy, M., Richardson, T.J., Craythorne, E., Mallipeddi, R. and Coleman, A.J. (2014) "Motion tracking to enable pre-surgical margin mapping in basal cell carcinoma using optical imaging modalities: initial feasibility study using optical coherence tomography."                                                                  In SPIE BiOS (pp. 893516-893516). International Society for Optics and Photonics. Link

Alawi, S.A., (2014) "Optische Kohärenztomografie zur präoperativen Evaluation bei nicht melanozytären Hauttumoren"                                                      (Doctoral dissertation, Freie Universität Berlin) Link

Wang, K. X., et al. (2013) "Optical coherence tomography-based optimization of mohs micrographic surgery of Basal cell carcinoma: a pilot study"     Dermatol Surg, 39(4), pp. 627-633 doi: 10.1111/dsu.12093. Link

Pelosini, L., et al. (2013) "In vivo optical coherence tomography (OCT) in periocular basal cell carcinoma: correlations between in vivo OCT images and postoperative histology" Br J Ophthalmol, doi: 10.1136/bjophthalmol-2012-303043. Link

Pomerantz, R., Zell, D., McKenzie, G. and Siegel, D.M., 2011. "Optical coherence tomography used as a modality to delineate basal cell carcinoma prior to Mohs micrographic surgery." Case reports in dermatology, 3(3), pp.212-218. Link

 

 

Non-melanoma skin cancer & actinic keratosis - Treatment monitoring

Updated January 2018

Markowitz, O., Wang, K., Levine, A., Schwartz, M., Minhas, S., Feldman, E. and Siegel, D.M. (2017) "Noninvasive Long-term Monitoring of Actinic Keratosis and Field Cancerization Following Treatment with Ingenol Mebutate Gel 0.015%."                                                                                         The Journal of clinical and aesthetic dermatology, 10(10), p.28. Link

Niculescu, L., Bierhoff, E., Hartmann, D., Ruzicka, T., Berking, C. and von Braunmühl, T. (2017) "Optical coherence tomography imaging of basal cell carcinoma undergoing photodynamic therapy: A pilot study." Photodiagnosis and Photodynamic Therapy, 18, pp.133-137. Link

Mollan, S.P., Keane, P.A. and Denniston, A.K. (2017)                                                                                                                                                                    "The use of transdermal optical coherence tomography to image the superficial temporal arteries." Eye, 31(1), pp.157-160. Link

Banzhaf, C.A., Thaysen‐Petersen, D., Bay, C., Philipsen, P.A., Mogensen, M., Prow, T. and Haedersdal, M. (2016) "Fractional laser‐assisted drug uptake: Impact of time‐related topical application to achieve enhanced delivery." Lasers in surgery and medicine. Link

Markowitz, O. and Schwartz, M. (2016) "The Use of Noninvasive Optical Coherence Tomography to Monitor the Treatment Progress of Vismodegib and Imiquimod 5% Cream in a Transplant Patient with Advanced Basal Cell Carcinoma of the Nose."                                                                                                     The Journal of Clinical and Aesthetic Dermatology, 9(8), p.37. Link

Markowitz, O., Schwartz, M., Feldman, E., Bieber, A., Bienenfeld, A., Nandanan, N. and Siegel, D.M. (2016) "Defining field cancerization of the skin using noninvasive optical coherence tomography imaging to detect and monitor actinic keratosis in ingenol mebutate 0.015%-treated patients." The Journal of Clinical and Aesthetic Dermatology, 9(5), p.18. Link

Levine, A., Wang, K. and Markowitz, O. (2016)                                                                                                                                                                                  "Optical Coherence Tomography for Skin Cancer Screening." Gavin J Dermatol Res Ther, 2016, pp.24-25. Link

Braunmühl, T., Hartmann, D., Tietze, J.K., Cekovic, D., Kunte, C., Ruzicka, T., Berking, C. and Sattler, E.C. (2016)                                                                                  "Morphologic features of basal cell carcinoma using the en‐face mode in frequency domain optical coherence tomography."                                          Journal of the European Academy of Dermatology and Venereology, 30(11), pp.1919-1925. Link

Olsen, J., Themstrup, L., De Carvalho, N., Mogensen, M., Pellacani, G. and Jemec, G.B.E. (2016) "Diagnostic accuracy of optical coherence tomography in actinic keratosis and basal cell carcinoma." Photodiagnosis and Photodynamic Therapy, 16, pp.44-49. Link

Yücel, D., Themstrup, L., Manfredi, M. and Jemec, G.B.E. (2016).                                                                                                                                                   "Optical coherence tomography of basal cell carcinoma: density and signal attenuation." Skin Research and Technology. Link

Schwartz, M., Siegel, D.M. and Markowitz, O. (2016)                                                                                                                                                     "Commentary on the Diagnostic Utility of Non‐invasive Imaging Devices for Field Cancerization."  Experimental dermatology. Link

Markowitz, O. & Utz, S. (2015) "Differentiating Early Stage Cystic Keratoacanthoma, Nodular Basal Cell Carcinoma, and Excoriated Acne Vulgaris by    Clinical Exam, Dermoscopy, and Optical Coherence Tomography: A Report of 3 Cases" Journal of Clinical and Aesthetic Dermatology, 8(4), pp. 48-50. Link

Themstrup, L., et al. (2013) "Optical Coherence Tomography Imaging of Non-melanoma Skin Cancer Undergoing Photodynamic Therapy RevealsSubclinical Residual Lesions" Photodiagnosis Photodyn Ther, doi: 10.1016/j.pdpdt.2013.11.003. Link

Banzhaf, C. A., et al. (2013) "Optical coherence tomography imaging of non-melanoma skin cancer undergoing imiquimod therapy"                                         Skin Research and Technology, doi: 10.1111/srt.12102. Link

Schmitz, L., Bierhoff, E. and Dirschka, T. (2013) "Optical coherence tomography imaging of Erythroplasia of Queyrat and treatment with                     imiquimod 5% cream: A case report." Dermatology, 228(1), pp.24-26. Link

Markowitz, O., Schwartz, M., Feldman, E., Bieber, A., Bienenfeld, A., Nandanan, N. and Siegel, D.M. (2016) "Defining field cancerization of the skin using noninvasive optical coherence tomography imaging to detect and monitor actinic keratosis in ingenol mebutate 0.015%-treated patients."                           The Journal of Clinical and Aesthetic Dermatology, 9(5), p.18. Link

Maier, T., et al. (2015) “Treatment monitoring of topical ingenol mebutate in actinic keratoses with the combination of optical coherence tomography and reflectance confocal microscopy: a case series” JEADV. Link